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Natural anti-inflammatory chitosan oligosaccharide

RENGTY Chitosan oligosaccharide is natural alkaline oligosaccharides extracted from the shell of snow-crab and hydrolyzed chitosan by bio enzymolysis, it is a amino small molecules oligosaccharide with positive charge, whose molecular weight is under 3000DA, with good water-solubility, safe, nontoxic and easily absorbed by animal, because the chemical structure is very similar to plant fibers, it’s called edible animal cellulose.

Key Words:

chitosan oligosaccharide chitosan oligosaccharide for poultry chitosan oligosaccharide powder Natural anti-inflammator

Category：

Application

Poultry

E-mail:

susan.lee@rengty.com

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Natural anti-inflammatory chitosan oligosaccharide

Natural anti-inflammatory chitosan oligosaccharide

Description

Chitosan oligosaccharide is a functional carbohydrate, which can be used as signal molecule, regulates the processes of immune, reproduction, diseases and so on. By the research of its structure, function, production and quality control, potimized and applied as feeds, drugs and vaccines, it can improve animal production performance, increase production efficiency and create economic value.

As a new feed additive, chitosan oligosaccharide can improve the production performance of pigs, poultry and aquatic animals, improve the immunity of the organism, and play the biological function of antibacterial and anti-inflammatory. It can be used as an effective substitute for feed antibiotics growth promoter, which opens up a new way for the development of new pollution-free green feed additives in feed industry.

Specification

Product name	Chitosan oligosaccharide
Key component	Chitosan oligosaccharide, maltodextrin
Appearance	Light yellow powder
Particle size	Residual is less than 0.5% on the standard sieve of 0.25mm
Glucosamine (NAG)	≥10%
Aroma	Sour odor
Water solubility	100% soluble in water
Moisture	≤10%
Ash	≤1.5%
Arsenic (As)	≤3.0 mg/kg
Plumbum (Pb)	≤5.0 mg/kg
Total plate count	≤2.0x10⁶ CFU/g
Total mould count	≤2.0x10⁴ CFU/g
Salmonella	Negative

Function

Anti-inflammatory, reduce the secretion of inflammatory factors, replace chlorotetracycline, reduce antibiotic dosage.
Improve animal antibody levels
Prevention of enteritis. Reduce the incidence of feed stool and watery stool
Reduce the occurrence of salpingitis, reduce the rate of broken eggs and death rate.
Increase feed intake, improve feed conversion rate of meat and eggs.

Availability in broiler trial

Effect of chitosan oligosaccharide on production performance of Broiler

Items		Control group	Test Group (500g/t)
0-21 days	ADG (g)	26	28
	ADFI (g)	40	42
	F:G	1.54	1.49
22-42 days	ADG (g)	55	62
	ADFI (g)	123	134
	F:G	2.23	2.16
0-42 days	ADG (g)	41	45
	ADFI (g)	82	87
	F:G	2.01	1.91

Effect of chitosan oligosaccharide on immune organ of Broiler

Items	Control Group	Test Group (500g/t)
Bursa index	2.14	2.66
Thymus index	3.69	4.26
Spleen index	1.16	1.34

Effect of chitosan oligosaccharide on blood immunity of Broiler

Items		Control group	Test Group (500g/t)
21 days	IgA	2.03	2.48
	IgM	1.45	1.64
	IgG	3.89	4.52
	T	0.52	0.43
42 days	IgA	2.03	2.48
	IgM	1.45	1.64
	IgG	3.89	4.52
	T	0.52	0.43

Effect of chitosan oligosaccharide on intestinal volatile fatty acid content of Broiler

Items		Control group	Test Group (500g/t)
Acetic acid	Duodenum	5.39	6.9
	Jejunum	0.16	0.25
	Ileum	0.07	0.11
Propionic acid	Duodenum	16.07	34.2
	Jejunum	0.29	0.88
	Ileum	0.06	0.19
Isobutyric acid	Duodenum	15.34	30.07
	Jejunum	0.24	0.41
	Ileum	0.08	0.23

Chitosan oligosaccharide replace antibiotics

Treatment	Aureomycin dosage mg/kg^-1	Chitosan oligosaccharide dosage Mg/kg^-1			SEM	P-value
	50	50	100	150		treatment effect	Chitosan oligosaccharide
	50	50	100	150		treatment effect	One time	Two time
Average daily gain (ADG) /g
1-21 d	37.9±1.66	38.0±1.81	38.0±2.54	37.8±1.73	0.46	0.35	0.61	0.18
22-42d	57.1±6.71^b	57.7±5.01^b	63.2±5.72^a	63.0±5.33^a	1.22	0.03	0.47	0.04
1-42d	47.2±3.65^b	47.9±4.03^b	50.5±3.48^a	50.4±2.76^a	1.05	0.05	0.18	0.05
Average Daily Feed Intake (ADFI) /g
1-21 d	47.1±2.59	47.0±2.14	47.0±3.01	47.1±1.69	0.64	0.84	0.90	0.82
22-42d	117.3±5.78^b	118.6±4.57^b	125.1±9.26^a	124.0±7.01^a	0.95	0.04	0.07	0.05
1-42d	82.1±2.87^b	82.7±3.07^b	86.0±5.74^a	85.5±3.46^a	0.71	0.07	0.10	0.05
feed conversion rate (FCR)
1-21 d	1.24±0.06	1.24±0.07	1.24±0.05	1.25±0.04	0.08	0.72	0.57	0.31
22-42d	2.05±0.27	2.06±0.35	1.98±0.22	1.94±0.07	0.07	0.69	0.10	0.22
1-42d	1.74±0.15	1.73±0.21	1.70±0.13	1.70±0.04	0.12	0.73	0.16	0.35

Conclusion: Adding 100 mg/kg or 150 mg/kg chitosan oligosaccharide into the diet of broiler obtained the same or better ADG, ADFI and FCR as aureomycin. It can be seen that the addition of chitosan oligosaccharide at a certain level in the diet of broilers has a better growth promoting effect and can be used to replace aureomycin in the diet of broilers. The optimal addition amount is 100 mg/kg.

Recommended dosage

Animal	Stage	Dosage (g/t)	Stage	Dosage (g/t)
Broiler	0-7 days	200-400	7-Slaughter	200-400
Layer	Brooding to breeding	300	Laying period	300

Packaging and Storage

Sample	20g/bag, 200g/bag, 300g/bag, 500g/bag, 1kg/bag, 2kg/bag, 5kg/bag
Packaging	20kg/bag, 20kg/drum or as requirements.
Pallet	If 20kg/bag, 1000kg/50bag/pallet
Container	One 20'GP can contain 10-14 tons if bag
Storage	Stored 24 months sealed in a cool, dry and airy place

Delivery

Port of loading: Qingdao or any port of China as requirements

Delivery time: 10-20 days shipment after signed contract

By Express

By Air

By sea

By land

Suitable for under 50kg

Fast: 3-7 days

High cost

Door to door service

Easy to pick up the goods

Suitable for more than 50kg

Fast: 3-7 days

High cost

Port to port service

Professional broker needed

Suitable for more than 500kg

Slow: 7-45 days

Low cost

Port to port service

Profissional broker needed

Suitable for more than 500kg

When by sea can not arrive at you, you can select land transportation, by train or by motor

General speaking, EMS, TNT, DHL, UPS by express, by air and by sea is main shipping terms.

By express for quantity less than 50kg cargo, also called DDU service

By sea for quantity over 500kg

By air is available for above 50kg

For high value products, please select air shipping or DHL express for safe

If the cargo quantity is more than 500kg, but by sea can not arrive at you, please select land transportation, by train or by motor.

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